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Nanoparticle-Based COVID-19 Vaccine Could Target Future Infectious Diseases

Nanoparticle-Based COVID-19 Vaccine Could Target Future Infectious Diseases

Just one dose of a new nanoparticle-based COVID-19 vaccine was enough to produce an immune response in animals on track with vaccines currently in clinical use. And with minor changes, Northwestern University investigators hope the same vaccine platform could target other infectious diseases.

SARS-CoV-2 Infection Increases Risk of Maternal Mortality and Obstetric Complications

Pregnant and postpartum individuals infected with SARS-CoV-2 during pregnancy have an increased risk of maternal mortality or morbidity from obstetric complications, according to a recent study published in JAMA.

Why COVID-19 Surveillance in Nigeria Is Critical

If the United States ignores COVID-19 in Nigeria, we forgo global genomic surveillance at our own peril, reports a new Northwestern Medicine study published in Nature Communications.

Nano Bubbles Could Treat, Prevent Current and Future Strains Of SARS-Cov-2

Northwestern Medicine scientists and collaborators at The University of Texas MD Anderson Cancer Center have identified natural nano-bubbles containing the ACE2 protein (evACE2) in the blood of COVID-19 patients and discovered these nano-sized particles can block infection from broad strains of SARS-CoV-2 virus in preclinical studies.

COVID-19 Boosters Increase Protection with Alexis Demonbreun, PhD

Northwestern Scientists Investigate COVID-19 Vaccines, Tests and Disparities

As the COVID-19 pandemic nears the two-year mark, Northwestern Medicine scientists continue to tackle every facet of the disease, from investigating coronavirus vaccines’ potential for providing immunity against similar coronaviruses to developing novel rapid antigen-based tests and examining disparities in COVID-19 case and mortality rates in Chicago.  

Boosters increase protection over full vaccine dose

A new Northwestern University study on the effectiveness of COVID-19 boosters shows they generate a stronger antibody response than after a full two-dose vaccination. These are the first findings showing the antibody response to booster doses is much larger than the response after the second vaccine dose and even higher than the responses among people … Continued

AstraZeneca’s vaccine dosing ‘mistake’ led to new dosage finding in mice

A dosing error made during an AstraZeneca-University of Oxford COVID-19 vaccine trial has led to a new dosage finding in mice, reports a new Northwestern Medicine study. During the AstraZeneca-Oxford trial, some human participants erroneously received a half dose of their first shot, followed by a full dose for their second shot. Paradoxically, the trial … Continued

Majority of unvaccinated Americans are concerned enough about COVID-19 to wear masks

While 29% of Americans are still unvaccinated, nearly two-thirds of this group (19%) are concerned enough about the spread of COVID-19 to regularly wear a mask, and the No. 1 reason for a large majority of them is concern about family members contracting COVID-19. A recent poll by a consortium of universities comprised of Northwestern, … Continued

One coronavirus vaccine may protect against other coronaviruses

Northwestern Medicine scientists have shown for the first time that coronavirus vaccines and prior coronavirus infections can provide broad immunity against other, similar coronaviruses. The findings build a rationale for universal coronavirus vaccines that could prove useful in the face of future epidemics. “Until our study, what hasn’t been clear is if you get exposed … Continued