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Penn Researchers Discover Drug that Blocks Multiple SARS-CoV-2 Variants in Mice

A small molecule STING agonist was highly protective against the virus that causes COVID-19 and likely other coronaviruses

The drug diABZI — which activates the body′s innate immune response — was highly effective in preventing severe COVID-19 in mice that were infected with SARS-CoV-2, according to scientists in the Perelman School of Medicine at the University of Pennsylvania. The findings, published this month in Science Immunology, suggest that diABZI could also treat other respiratory coronaviruses.