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Inflammation, Rather Than Virus Provoking It, May Be Key to COVID-19 Loss of Smell

While the devastating impacts of COVID-mediated anosmia are well known, the biological mechanisms underlying the condition remain somewhat of a mystery. In a study published today in JAMA Neurology, a Johns Hopkins Medicine-led team shows that loss of smell is most likely a secondary consequence of inflammation occurring when the body’s immune system responds to SARS-CoV-2 infection rather than a direct action of the virus.