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“Ultra-potent” antibody against COVID-19 variants isolated at VUMC

“Ultra-potent” antibody against COVID-19 variants isolated at VUMC

A technology developed at Vanderbilt University Medical Center has led to the discovery of an “ultra-potent” monoclonal antibody against multiple variants of SARS-CoV-2, the virus responsible for COVID-19, including the delta variant. The antibody has rare characteristics that make it a valuable addition to the limited set of broadly reactive antibody therapeutic candidates, researchers reported … Continued

“Vanderbilt Health DNA: Discoveries in Action” Podcast

The first episode of the second season of Vanderbilt University Medical Center’s original podcast series, Vanderbilt Health DNA: Discoveries in Action, tackles bold questions and issues pushed to the surface by COVID-19. This season, the award-winning 10-episode series delves into a host of topics, including the role of clinical trials in advancing medicine, equity and representation, … Continued

Rheumatoid arthritis drug combined with standard of care may help reduce mortality for hospitalized COVID-19 patients

Hospitalized patients with COVID-19 who received the rheumatoid arthritis drug baricitinib, in combination with the standard of care including corticosteroids, died less often than those receiving only the standard of care, according to a study released this week in The Lancet Respiratory Medicine. The study, led by principal investigators E. Wesley Ely, MD, MPH, Grant … Continued

Rheumatoid arthritis drug combined with standard of care may help reduce mortality for hospitalized COVID-19 patients

Hospitalized patients with COVID-19 who received the rheumatoid arthritis drug baricitinib, in combination with the standard of care including corticosteroids, died less often than those receiving only the standard of care, according to a study released this week in The Lancet Respiratory Medicine. The study, led by principal investigators E. Wesley Ely, MD, MPH, Grant … Continued

COVID-19 antibody ‘cocktail’ discovered at VUMC protects chronically ill: study

A monoclonal antibody cocktail against the COVID-19 virus discovered at Vanderbilt University Medical Center and developed by AstraZeneca reduced the risk of symptoms in a study of immunocompromised and chronically ill adults later exposed to the virus by 77%, the company announced today. Based on the positive results from the PROVENT Phase III trial, the … Continued

Memphis teens lead surge in Tennessee COVID vaccinations

Memphis teens have been leading Tennessee’s surge of recent COVID-19 vaccinations, The Commercial Appeal reported. The 15-19 age group in the Memphis region showed the greatest growth of any age group across the state’s eight regions from late July through last week, according to a new study by researchers at the Department of Health Policy at … Continued

Vanderbilt’s findings 5 months after opening clinic for COVID-19 long haulers

As Delta numbers continue to surge, some patients are still working to recover from the first round of COVID-19 weeks and months after having the virus. Vanderbilt University Medical Center opened its doors to a clinic specifically dedicated to these patients roughly five months ago. So far, Vanderbilt reports brain fog, fatigue, and cognitive impairment as … Continued

Study finds genetic risk factors for severe COVID-19 illness

A massive worldwide collaboration including researchers from Vanderbilt University Medical Center (VUMC) has identified several genetic factors associated with SARS-CoV-2 infection and severe COVID-19 illness. The findings from nearly 50,000 COVID-19 patients and 2 million uninfected controls, published July 8 in the journal Nature, could lead to new treatments and demonstrates the power of genetic studies … Continued

Ask an Expert: Do I need to get vaccinated even if I had COVID-19?

Thomas Talbot, professor of medicine and chief hospital epidemiologist at Vanderbilt University Medical Center, shares why it’s important for people to get vaccinated, even if they’ve already had COVID-19.

COVID-19 complication underdiagnosed

Multisystem inflammatory syndrome (MIS) is the inflammation of various tissues and has been cited as a complication of SARS-CoV-2 infection. Originally identified in children, a form of MIS has since been described in adults (MIS-A). Giovanni Davogustto, MD, and colleagues at Vanderbilt University Medical Center identified and collected characteristics of adult patients at risk of MIS-A … Continued